If you think about 'chance' human agency begins to change.

 Once you get interested in chance, your sense of human agency begins to change. People have to find ways of describing the (new) fact that, like everything else in nature, they are nothing special. 

Even the people who are considered to be especially good at this kind of description, the writers and painters, are nothing special.

Source: http://www.lrb.co.uk/v25/n10/adam-phillips/hauteur