Can we derive ought from ís? Yes. we can

From the perspective of neuroscience and brain evolution, the routine rejection of scientific approaches to moral behaviour based on Hume’s warning against deriving ought from is seems unfortunate, especially as the warning is limited to deductive inferences.
The dictum can be set aside for a deeper, albeit programmatic, neurobiological perspective on what reasoning and problem-solving are, how social navigation works, how evaluation is accomplished by nervous systems, and how mammalian brains make decisions.
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”— Patricia Churchland in her book Braintrust (emphasis added)