Inalienable components of self and the commodifiable bits of not-self?

What place in our social classifications is to be made for the hybrid entities that bio-medicine is ushering into being – prosthetic, transfused, transplanted, transgenic? Who are we as biological entities, and how do we make descriptive and prescriptive distinctions between the inalienable components of self and the commodifiable bits of not-self? 

So technology bio medical research will carry on apace as to the objections to this advance
a humanism that is highly suspicious of human intervention is a Luddite humanism that has lost its nerve.